Rücktitelbild: PD‐L1 Aptamer‐Functionalized Metal–Organic Framework Nanoparticles for Robust Photo‐Immunotherapy against Cancer with Enhanced Safety (Angew. Chem. 5/2023)
نویسندگان
چکیده
PD-L1 aptamer-based spherical nucleic acids (SNAs) were designed that consist of oxaliplatin (OXA) encapsulated in a metal–organic framework (MOF) nanoparticle core and dense shell aptamer (denoted as M@O-A), reported by Zhengyu Jin, Jie Tian, Yang Du, co-workers their Research Article (e202214750). Upon light irradiation, the versatile M@O-A allows for robust photo-immunotherapy against cancer combining photodynamic therapy, chemotherapy, immunotherapy one nanoplatform with reduced immunotoxicity.
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ژورنال
عنوان ژورنال: Angewandte Chemie
سال: 2023
ISSN: ['1521-3773', '1433-7851', '0570-0833']
DOI: https://doi.org/10.1002/ange.202218931